Around 80 guests attended the launch of golden anniversary celebrations for charity SASBAH - the Sussex Association for Spina Bifida and Hydrocephalus based at Gun Hill.
It held an event for VIPS, service users and friends at Bedes School.
Host was BBC newsreader Ian Palmer and guests included the High Sheriff of East Sussex Chris Gebbie, county council chair Colin Belsey and Councillor Tony Nicholson, chair of Lewes District Council.
Chief Executive Rom Sanglaji said: “It was a very well attended evening and gave us the opportunity to show everyone a taste of what we do.
“We are very proud to have reached 50 and during the year we will be out and about throughout the county spreading that very positive message.”
The charity is based at Gun Hill, near to both Horam and Chiddingly, and has developed massively since it was formed in 1965, now supporting around 500 disabled people in Sussex.
It also runs SASPIRE, a social enterprise which offers valuable work experience opportunities to its service users, at its office in East Sussex, and also at its West Sussex base.
Rom added: “We are keen to promote the work that we do, and would be delighted to hear from anyone who would wish to become involved.”
If you would like to volunteer at the charity: email@example.com.