Lego and Sylvanian Family toys valued at several thousand pounds were stolen from a shop in Seaford.
Burglars entered IT shop Red Rooster IT and then made a hole through an internal wall to gain access to Toytown.
Police are appealing for information about the burglaries which took place in the High Street overnight between Sunday February 16 and Monday February 17.
PC Duncan Ford said; “It is possible that the burglars used a vehicle to remove the stolen toys which are all boxed and brand new.
“If anybody saw any suspicious activity in the vicinity of the properties on Sunday evening or overnight, especially at the rear, we would like to hear from them.
“Did you see a vehicle or anybody carrying boxes of toys?
“If you are offered any new boxed Lego or Sylvanian Toys, or know anybody who has suddenly acquired quantities of them please contact is via 101 or email email@example.com quoting serial 239 of 17/2.
“You can also call the independent charity Crimestoppers anonymously via 0800 555 111.”
The burglaries took place between 4pm on Sunday 16 February and 8.50am the following morning,
Red Rooster IT and a neighbouring property Toytown were entered after a door to flats at the back was forced open.
The intruders then entered the IT shop via a window but at this stage it is not clear whether anything was stolen.
They made a hole through an internal wall in a communal entrance hall, to get into the toyshop.
Once inside they also forced open the till and stole about £900 cash.