Police were called to a road traffic collision on the B2104 Hailsham Road, near Stone Cross, involving a car and a motorcycle at 5.23pm on Tuesday.
The accident occurred outside the Holly Blue restaurant.
The Kent, Surrey and Sussex Air Ambulance was alerted but the motorcyclist, a 17-year-old girl, sustained only slight injuries. The car driver was unhurt.
The road was closed between Hailsham and Stone Cross for approximately an hour while the incident was dealt with, causing rush hour traffic to build at both ends of the closure.