A beach clean event will be taking place at Birling Gap and Cuckmere Haven from September 19 until September 22.
The Marine Conservation Society (MCS) is looking for people to join beach cleans around the county coastline.
The marine charity said it hopes people who love the coast around Sussex will take part in a nationwide beach clean event.
The MCS runs regular beach cleans around the UK which this year will culminate in the Great British Beach Clean.
The charity said it hoped to get a record number of people cleaning beaches around the UK during its Great British Beach Clean weekend and is looking for volunteers in Sussex.
Tom Bell, MCS campaigns manager, said: “Our domestic habits over the last 50 years or so have resulted in dirty beaches. We throw more stuff away than ever. Plastic in the marine environment may take hundreds of years to break down and it washes up or is blown onto beaches in bits from micro pieces to larger chunks.
“We flush stuff down the loo we shouldn’t, and that ends up in our water ways and then our beaches. We want to see people turning out to clean up their favourite or local beach during our Great British Beach Clean weekend – please don’t turn your back on our beaches.”
There are beach clean events in East Sussex at Birling Gap, Brighton, Cliff end, Cuckmere Haven, Holywell, Rottingdean, Rye Harbour, Tidemills, Brighton Marina, Pett Level and Cow Gap.
To find out dates and times at individual beaches and to sign up to the Great British Beach Clean register at www.mcsuk.org/greatbritishbeachclean or call 01989 567807