A Hassocks cyclist was airlifted to hospital with serious injuries following a collision in Barcombe, police said.
Officers are seeking witnesses to the collision which happened in Spithurst Road on Friday (April 12).
A Sussex Police spokesman said: “Shortly before noon on Spithurst Road a cyclist and a black Honda Jazz collided. The cyclist, a 53-year-old woman from Hassocks, was airlifted to St George’s Hospital, London with serious injuries.
“Anyone who saw what happened is asked to contact police online quoting Operation Crouch.”