The Explosive Ordance Disposal unit (EOD) was called after a ‘suspicious package’ was found in Dewe Road, Brighton.
A controlled explosion was carried out, police confirmed.
The team is continuing to assess the scene.
Dewe Road remains closed and a surrounding cordon remains in place.
Affected homes and buildings remain evacuated, police said.
However the A70 Lewes Road has now reopened in both directions.
Police apologised for the disruption caused.
More to follow.