A woman received serious but non life threatening injuries after her silver Ford Puma was in collision with a silver Nissan on the A27, near Drusillas on Saturday May 4.
Sussex Police and emergency services including East Sussex Fire and Rescue Service, attended the scene near Sherman Bridge at around 11.20am.
It is thought that the 51-year-old woman from Eastbourne, who was driving the Ford Puma, was travelling west and veered across into the opposite carriageway, causing it to collide head-on with the Nissan travelling east.
The driver of the Nissan and her passenger, both aged 69 and from Folkington, were also taken to hospital with minor injuries.
Sergeant Melanie Doyle from the Road Policing Investigation Team said: “The injured woman remains at the Royal Sussex County Hospital and is being treated for multiple fractures to her body.
“I would appeal to any other drivers who witnessed the collision to please call 101 quoting Op Belgrade.”
“Sussex Police would like to thank drivers for their patience as the road was closed both ways for several hours whilst the casualties were attended to and the road cleared of debris.”