Officers said they received a report of a collision at around 10.30am on Monday, June 27.
A Sussex Police spokesperson said, “The collision involved multiple vehicles and resulted in a road closure in both directions. It has since re-opened.
“A woman, driving one of the vehicles, was taken to hospital with potentially life-changing injuries.
“Anyone with dashcam footage or information is urged to email [email protected], quoting serial 491 of 27/06.”