Haven Road, Billingshurst, was closed between Blue Ship Road and the A281 Guildford Road shortly after the collision was reported at 8.50am on Saturday (April 24).
Police said they were called to a report of a collision between a car and a motorbike on Haven Road, Billingshurst.
A spokesman said one man has been taken to hospital with serious injuries.
“The road was closed temporarily to allow emergency services to attend the scene, and for both vehicles to be recovered,” the spokesman added.
The road has since reopened.