Four fire engines from West Sussex Fire and Rescue Service were called to the scene at 8.40pm last night.
Two derelict buildings were on fire and Brighton Road had to be closed while firefighters battled the flames.
The fire service did not leave the scene until 2am this morning after ensuring the scene had been made safe.
Fire experts returned to the area this morning to reinspect the damage.
The cause of the fire remains unknown, as well as the extent of the damage to the buildings.
No injuries were reported.