Police are advising drivers of long delays in the Polegate to Lewes area around the A27 this afternoon (Thursday March 5) which they say are likely to extend into the evening rush hour.
Emergency services have been at the scene since 11.40am when a 41-ton lorry with a load of aluminium overturned on to its side on the westbound A27 outside Folkington Manor between Polegate and Drusillas roundabout, and collided with a car.
Several other vehicles sustained minor damage.
The driver has been taken to the Royal Sussex County Hospital in Brighton for treatment. There is no information on his condition at this stage.
At the other end of the county a woman is seriously injured after a crash on the A27 at Chichester.
The accident happened around 1.15pm on the Fishbourne Roundabout after a lorry carrying a mobile home collided with a car.
The woman – believed to be driving the car – had to be extricated by firefighters and has been airlifted to hospital.
The A27 eastbound is shut and traffic is being diverted along Terminus Road.