More than 2,500 runners have registered to take part, with some of the fastest elite field competitors hitting the start line for the 28th edition of the race.
Last year’s winner and local favourite Jake Leitch (Worthing Harriers) is hoping a niggling injury settles down as he looks to defend his crown.
Leitch will face tough competition as a number of the counties elite Tom Evans (Lewes), James Westlake, Paul Navesey and Neil Boniface (all Crawley) and Kevin Rojas (Brighton & Hove) will battle it out to be crowned 2018 champion.
In the female race, 2017 winner Emily Proto will start as favourite.
A record number of 2,800 runners are registered for the Worthing 10k.
The race starts on Worthing Promenade at 9.30am. Road closures will be in place from 9.15am through till 11am.
Further information can be found by visiting www.worthing10k.co.uk