All six goals came in a breathless first half as Jamie Hollis’ side scored first and last – but let in four in between.
Harry Docherty gave Lancing an 11th minute lead before the hosts were stunned to let in four in 11 minutes, scored by Alex Kozak, Leonardo Luis De Carvalho Pedro, Jaime Obama Nvumba and Derek O'Halem.
Docherty struck again from the spot ten minutes before the break to spark hopes of a Lancers comeback but there was no further scoring and it was the east London side who went through.
See pictures by Stephen Goodger on this page and the ones linked and get the local football action in the Worthing Herald, out on Thursday.
1. Lancing v Athletic Newham in the FA Cup pictures by Stephen Goodger (26).jpeg
Lancing v Athletic Newham in the FA Cup Photo: Stephen Goodger
2. Lancing v Athletic Newham in the FA Cup pictures by Stephen Goodger (24).jpeg
Lancing v Athletic Newham in the FA Cup Photo: Stephen Goodger
3. Lancing v Athletic Newham in the FA Cup pictures by Stephen Goodger (25).jpeg
Lancing v Athletic Newham in the FA Cup Photo: Stephen Goodger
4. Lancing v Athletic Newham in the FA Cup pictures by Stephen Goodger (19).jpeg
Lancing v Athletic Newham in the FA Cup Photo: Stephen Goodger