Three of the games are taking place in Bexhill and two of them are county cup quarter-finals.
Sidley United host Shoreham in the last eight of the Sussex County League John O’Hara League Cup, while Little Common entertain high-flying East Preston at the same stage of the Sussex RUR Charity Cup.
Both Sidley are Shoreham will be on something of a high having ended winless runs at the weekend. A tight game is in prospect with Sidley ahead of Shoreham on goal difference in the Sussex County League Division One table.
Sidley, for whom goalkeeper Greg Nessling is a fitness doubt, will be seeking a measure of revenge having lost 5-1 in a league fixture away to Shoreham during September. The winners will face Peacehaven & Telscombe in the semi-finals.
Sussex Division Two high-flyers Common will be out to spring a surprise against Division One title hopefuls East Preston and set up a last four tie against the aforementioned Peacehaven.
Common knocked out one high-riding Division One side in Hassocks in round two and took Crowborough Athletic, who are already through to the semi-finals, to penalties in the Sussex Senior Cup.
Rye United will continue their Sussex Division One campaign at home to Crowborough. Seventh-placed Rye thrashed mid-table Crowborough three times last season and beat them again in August’s reverse fixture.
Bexhill United are at home to Eastbourne United AFC in Sussex Division Two. Seventh-placed Bexhill are seven points and four positions behind their visitors, with whom they fought out a 2-2 draw in August’s reverse fixture.
The games involving Rye, Sidley and Bexhill kick-off at 7.45pm, while Common’s match gets under way at 7.15pm.