Potter will be without five established first teamers as the lowly Seagulls aim for their first victory since their 2-1 triumph at Aston Villa way back in November.
Aaron Connolly (hamstring), Tariq Lamptey (hamstring), Danny Welbeck (knee), Adam Lallana (illness) and Alireza Jahanbakhsh are all unavailable to face a Leeds team who have made a solid start to life in the Premier League.
Albion's Ben White is set for a reunion against a team where he spent a highly successful season long loan last campaign. There could also be another starting role for South African striker Percy Tau who impressed at Man City in midweek.
Scroll down and clock through to see how Potter's men could line-up.
1. Robert Sanchez
The 23-year-old Spaniard has looked calm and assured since replacing Maty Ryan as the regular No 1. Produced a number of fine saves during the 1-0 loss at City in midweek and difficult to see Ryan forcing his way back in at this rate
2. Joel Veltman
If Graham Potter goes with four at the back I fully expect Joel Veltman to slot in at right back. The Dutch international has been a sound addition following his 900k summer arrival from Ajax
3. Adam Webster
Has been excellent of late and really starting to prove his worth to this Albion team following his big money arrival at the start of last season. Sill gets a hard time from some fans which is quite surprising
4. Lewis Dunk
Vital to the way Brighton play. Very good defensively and distribution from the back as sound as ever. Will need to be at his best once more against a dangerous Leeds United attack