Mali international midfielder Yves Bissouma is suspended while experienced campaigner Dale Stephens this week completed a £1m switch to Burnley.
Scroll down and click through to see how we think Graham Potter could tweak his line-up against United.
1. Maty Ryan
A welcome clean sheet for the Aussie against Newcastle but will expect a sterner test against a potent Man United attack, still smarting from their loss against Palace last week
2. Ben White
The defender impressed against Chelsea and Newcastle and I'm looking forward to his match-up with Marcus Rashford
3. Lewis Dunk
The reliable skipper will no doubt take his place at the heart of a three man defence
4. Adam Webster
Has performed well so far this season on the left side of a three man defence
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