It's expected to be a highly charged atmosphere and yesterday, De Zerbi stressed the importance of the role Brighton fans will play. Three points against Southampton will seal at least a Europe Conference League place, with two games to spare.
A win would all-but take sixth position – a Europa league spot – as Brighton’s have a superior goal difference to Aston Villa, who the y play on the final day of the season.
"It’s the only game in our head," said De Zerbi. "To qualify for Europe we have to win two games. We need our fans; they have to help us and are crucial. If we win we win together. I expect one of the most difficult games of the season. Southampton scored three goals at Arsenal and have made many points away so I expect a very tough game."Here's the players who are in who is out of Brighton's crunch clash at the Amex Stadium...
1. Adam Lallana - out
A thigh injury ruled the former Liverpool man out for the rest of the season. Photo: Ryan Pierse
2. Solly March - out
A hamstring injury sustained against Everton keeps the winger out Photo: Mike Hewitt
3. Tariq Lamptey - out
A knee injury picked up against West Ham in March keeps him out Photo: Steve Bardens
4. Adam Webster - out
Continues his fitness trouble's but De Zerbi expects him back to face Man City Photo: Mike Hewitt