It's certain to be a highly-charged atmosphere at the famous old ground as Gerrard takes charge of Villa for the first time since his arrival from Rangers.
Gerrard was installed as the Villa boss after Dean Smith was sacked following a run of five consecutive defeats.
Potter's Brighton however have been in good form this season and sit seventh in the Premier League table.
Albion will be without suspended goalkeeper Robert Sanchez and Potter will have to decide whether to recall striker Neal Maupay into the team.
Scroll down and click through to see how Albion could line-up for this one.
1. Jason Steele
Will make his first Premier League appearance this season as a replacement to the suspended Rob Sanchez. "I have absolute faith in Jason," said Potter. "No problem at all."
2. Shane Duffy
Has been one of Albion's best players this season after his return from Celtic
3. Lewis Dunk
Continues to be overlooked for England but performs at a consistently high level for Albion
4. Adam Webster
Back from injury and the defender could make his first start since Brentford