Albion confirmed last week that injury-hit Colombian winger Jose Izquierdo will depart at the end of this month and further players are likely to follow now the transfer window is open.
Head coach Graham Potter will be keen to streamline his squad which would free up funds to enable him to strengthen in attacking areas.
Big decisions need to made on a number of players who were out on loan season and also players who continue to be on the fringes of the first team squad.
Brighton will also brace themselves for huge incoming bids for Yves Bissouma and England international defender Ben White.
Scroll down and click through to see the 12 key players who face an uncertain summer
1. Davy Propper
Brighton contract expires June 2023. The Dutch international hardly featured last season due to injury and illness. A classy operator at his best but faces stiff competition in central midfield from Yves Bissouma, Adam Lallana, Pascal Gross and now Jakub Moder and Caicedo. Would like to see him stay and get back to his best but the 29-year-old may favour a move to back to Holland with PSV said to be keen.
2. Jayson Molumby
Brighton contract expires June 2023. The Ireland international midfielder did not enjoyed enough game time at Preston following his January loan switch. Albion are well stacked in central midfield and will have to make a big decision on Molumby, 21, this summer. Molumby, who enjoyed a successful loan at Millwall the previous season, will be keen to play regular football be that on another loan or a permanent move away from the Amex.
3. Shane Duffy
Contracted with Brighton until June 2023. The Ireland international said he needs a ‘reset’ after a tough time north of the border while on loan with Celtic. The 29-year-old will likely move on this summer with Chris Hughton’s Nottingham Forest or Wayne Rooney’s Derby said to be possible destinations.
4. Maty Ryan
Brighton contract expires June 2022. The Aussie international lost his place between the sticks to Rob Sanchez and joined Arsenal on loan last January until the end of the season. Arsenal are said to be keen to complete a permanent deal this summer for around £5 million, which seems good business for all parties.