Between them they're involved in 14 extra preliminary round ties in which they'll be hoping to reach the first qualifying round.
There are two Sussex derbies - Lancing host Haywards Heath in an all-Isthmian south east division tie while Peacehaven entertain Crawley Down Gatwick in a clash of two SCFL sides.
As well as a place in the first of four qualifying rounds that precede the first round proper, this weekend's ties offer £1,444 in prize money to winning teams. Losing sides will get a consolation sum of £481.
The prize money goes up to £2.250 for teams who win in the first qualifying round. Teams from step three of the non-league pyramid - including the Isthmian premier division - enter the competition in the first qualifying round, with step one and two clubs joining in nearer to the first round proper.
Here are this weekend's ties involving clubs from Sussex and the SCFL - and as we wonder which local team, if any, can 'do a Chichester' and follow in the footsteps of the Oaklands Park team, who got to the second round proper two seasons ago, we say: Good luck to all teams involved. Look out for reports on our websites and in our papers.
Abbey Rangers v Loxwood
Bearsted v Burgess Hill Town
Beckenham Town v Hastings United
Kennington v Little Common
Lancing v Haywards Heath Town
Lingfield v Chertsey Town
Newhaven v Jersey Bulls
Peacehaven & Telscombe v Crawley Down Gatwick
Sheppey United v Saltdean United
South Park v Three Bridges
Steyning Town Community v Sutton Common Rovers
Sittingbourne v Littlehampton Town
Whitstable Town v Alfold
Winchester City v Chichester City
* Whitehawk have a bye into the first qualifying round after the withdrawal of their planned preliminary round opponents Whyteleafe.