The draw was broadcast by BBC Sussex and conducted by Paul Jeffery, Referee Development Officer, and Paul Baston, Finance Office.
Bognor will host Burgess Hill in a repeat of the 2019 final that the Rocks won after extra-time - that of course was the last SSC final to have been played, with last sason's competition abandoned in the lockdown before the Brighton-Eastbourne final could be played.
County league Bexhill have a plum tie away to Brighton's under-23s.
The following ties were drawn:
Midhurst & Easebourne vs. Crowborough Athletic
Oakwood vs. Lancing
Broadbridge Heath vs. Whitehawk
Hastings United vs. Eastbourne Borough
Pagham vs. Hailsham Town
Eastbourne Town vs. Shoreham
Horsham YMCA vs. Haywards Heath Town
Little Common vs. Lewes
Chichester City vs. Saltdean United
AFC Varndeanians vs. Langney Wanderers
Crawley Down Gatwick vs. Newhaven
Brighton & Hove Albion vs. Bexhill United
Peacehaven & Telscombe vs. Eastbourne United Association
Bognor Regis Town vs. Burgess Hill Town
Worthing vs. Three Bridges
East Grinstead Town vs. Horsham
Fixtures are to be played on or before Wednesday, November 4.