The incident happened on the southbound Golden Jubilee Way and has resulted in traffic backing up onto the A22 according to a Stagecoach South East social media post.
A spokesperson from Sussex Police said, “Around 8am on Thursday (May 13), police received a report of a three-vehicle collision on the southbound A22 Golden Jubilee Way, Eastbourne.
“No injuries have been reported to police.
“Motorists are asked to avoid the area if possible while recovery of the vehicles is arranged.”
South East Coast Ambulance Service has been contacted for a statement.