The A24 is closed northbound from Ashington B2133 to the Partridge Green junction with the B2135; and southbound from Buck Barn A272 to Dial Post, according to Sussex Roads Police.
At 2.35am Sussex Roads Police tweeted: “A24 closed both ways from Ashington to Buck Barn due to overturned container and large diesel spillage #cb149.”
Motorists should expect long delays.
More to follow.