Graham Potter will rotate his squad following Sunday's 3-0 victory at Newcastle and before Staurday's clash with Manchester United at the Amex.
Scroll down and click through to see how Albion may line-up at the Deepdale Stadium tonight
5. Bernardo
Scored his first senior goal for Brighton against Pompey last week in the Carabao and will hope to get forward down the left flank tonight
6. Alexis Mac Allister
Another to net his first goal for Albion against Portsmouth last week. Timed his run into the box well and planted home a firm header. Pushing for a starting place in the Premier League and the Argentina international will want to impress once again
7. Jayson Molumby
Played at right back last week against Portsmouth but with Dale Stephens said to be on his way to Burnley, Molumby could get his chance in central midfield
8. Davy Propper
Played 90 minutes against Portsmouth and will look to get more minutes as he regains full fitness after an Achilles problem. May well be need for Man U this Saturday with Bissouma suspended