Aside from Enock Mwepu’s sudden retirement, De Zerbi revealed he has no fresh injury concerns ahead of his side’s trip to face the Bees.
De Zerbi, who has overseen a 3-3 draw and 1-0 home defeat against Tottenham since replacing Graham Potter, added: “If you are fighting in the Premier League, you have to know that all games can be very difficult and you have to be ready to fight every opponent.
“We can suffer against Brentford because they are a good team. But we can play our football and they can suffer as well with our skill, ability and style of play.
“The last result (against Tottenham) was not fair and now we have the possibility to win the next game.”
Japan international Kaoru Mitoma is pushing hard for a starting role having impressed from the bench and flying wing back Tariq aAmptey is also keen to force his way in.
Here’s how Brighton could line-up in a 3-4-2-1 formation at Brentford...
5. WB - Tariq Lamptey
The former Chelsea man has been on the bench of late and De Zerbi may look to unleash his rapid wing back from the start at Brentford. Photo: Mike Hewitt
6. M - Alexis Mac Allister
Looks every inch a high quality Premier League player these days. Energy, skill, picks a pass and knows where the goal is. Top player! Photo: Bryn Lennon
7. M - Moises Caicedo
Continues to impress in his fledgling PL career. Easy to forget he's just 20 years of age. Photo: Mike Hewitt
8. WB - Solly March
March could be shifted to the left to allow Lamptey to bomb down the right. Playing the best football of his career. Photo: Tony Marshall