Graham Potter's Albion impressed last season with a ninth placed finish but lost key midfielder Yves Bissouma to Tottenham in a £30m deal. They also face the prospect of losing player of the year Marc Cucurella, who is wanted by Chelsea and Man City.
United have looked sharp in pre-season under Erik ten Hag and his first test against Albion at Old Trafford this weekend will be scrutinised by all United fans eager to see a drastic improvement on last season.
Man City, Chelsea and Liverpool have all strengthened this summer transfer window, while promoted teams Nottingham Forest, Bournemouth and Fulham add a fresh dynamic.
To test what potentially could happen in 2022/23, bonusfinder.co.uk put together the current squads based on the summer transfer activity and, using FIFA 22, simulated the upcoming Premier League season.
The simulation ran 200 times and produced an average table based on the results.
. BRIGHTON, ENGLAND - MAY 07: Scott McTominay of Manchester United in action with Danny Welbeck of Brighton & Hove Albion during the Premier League match between Brighton & Hove Albion and Manchester United at American Express Community Stadium on May 07, 2022 in Brighton, England. (Photo by Ash Donelon/Manchester United via Getty Images)
Brighton striker Danny Welbeck will be up against former club Manchester United on the opening day of the premier League season Photo: Ash Donelon
. 20th - AFC Bournemouth - 28 Pts
It looks bleak for AFC Bournemouth. Relegation back to the Championship was a usual outcome for a squad lacking Premier League proven quality. Photo: Mike Hewitt
. 19th - Crystal Palace - 31 Pts
According to FIFA, Patrick Viera’s second season in charge ended in relegation. Palace just seemed to get themselves in a rut that they couldn’t come back from regularly, a few more signings might be needed going into 22/23. Photo: Will Russell
. 18th - Southampton - 32 Pts
The simulations predict that Southampton’s 10 year stint in the Premier League will come to an end. They’ve finished in the bottom half for the past five seasons. Photo: Marc Atkins
. 17th - Fulham - 35 Pts
You suspect Fulham would take a 17th placed finish rather than going back to the Championship, it would be seen as a successful season. Photo: Paul Harding
. 16th - Brighton & Hove Albion - 39 Pts
Not sure about this one...It may be seen as a disappointment to Brighton fans going from 9th to 16th, but Premier League safety is the most important thing. Still lacking that firepower up front - according to FIFA Photo: Charlie Crowhurst
. 15th - Nottingham Forest - 40 Pts
Forest have been ambitious in the transfer window this summer and if they manage to avoid relegation it’ll all be worth it. Striker Taiwo Awoniyi will be key for Forest. Photo: Chris Brunskill
17. 4th - West Ham United - 68 Pts
If this happens it will be fully deserved for David Moyes and his players. They’ve quietly gone about their business in the transfer window and it paid dividends with that 4th spot finally secured on average. Photo: Justin Setterfield
18. 3rd - Chelsea - 69 Pts
Kai Havertz is the man to fill the void left by Romelu Lukaku. The simulations make him the key man in firing Chelsea towards any success. Photo: Henry Browne
19. 2nd - Manchester City - 79 Pts
Pep will not be happy with FIFA...although Erling Haaland took home the Golden Boot for 67% of the seasons, but it wasn’t enough to deal with the losses of Raheem Sterling and Gabriel Jesus. Photo: Mike Hewitt
20. 1st - Liverpool - 86 Pts
Liverpool ran out fairly comfortable winners in the end, Sadio Mane may be gone but in Lius Diaz they have a capable replacement. The Colombian and Mohammed Salah regularly combined for a hatful of goals each. Photo: Marc Atkins