The 24-year-old stepped up when the Seagulls were awarded a penalty in the 20th minute, but skewed his effort wide of the upright.
The Frenchman was then subbed off moments later after picking up a hamstring complaint, and became the first player to start a Premier League match, miss a spot-kick, and be taken off before half-time since Dennis Bergkamp in 1998.
Diogo Jota continued his impressive form in front of goal with a second-half strike that looked to have wrapped up all three points for the champions, but Graham Potter’s men were awarded a second penalty right at the death after a clumsy Andy Robertson challenge on Danny Welbeck. Pascal Gross subsequently converted.
At the time, many Liverpool supporters were sceptical as to how genuine Maupay’s injury was, however, with some suggesting that he'd done little more than bruise his ego.
We’ve gathered a selection of reactions from Kop fans below:
@manamandz16 tweeted: “Maupay so humiliated by a missed penalty even his hamstring pulled up to get him off the pitch”
@LFC_CapeTown tweeted: “Wonder if Maupay felt the injury before the pen but still wanted the glory.”
@TheLFCSD tweeted: “Maupay out with a sprained ego, we wish him a speedy recovery.”
@JonesSeniorLFC tweeted: “Maupay acting like a 3 year old. No way he’s injured.”
@57McNally tweeted: “Maupay; the first player in history to come off with embarrassment.”
@CraigFarquhar92 tweeted: “Yessss Maupay missing the penalty. Ya beauty. Huge let off.”
@ShaneBryne255 tweeted: “Maupay is a top red.”