This evenings visitors have never previously won at Old Trafford but Graham Potter's team will arrive full of confidence having won their lasttwo Premier League matches against Southampton and Newcastle.
United could however be without without striker Anthony Martial (knee) and defender Victor Lindelof (back). Both are doubts having missed training on Friday morning, while Solskjaer will also assess the fitness of Marcus Rashford and Mason Greenwood.
Paul Pogba could also return to the line-up having completed 90 minutes for France during the international break.
Scroll down and click through to see how United could line-up for this one
5. Luke Shaw
The England left back is enjoying his best season at United and a real threat in attacking areas too
6. Scott McTominay
A vital figure in the United midfield. Very athletic and mobile and provides a platform for the playmakers to shine. Very capable of driving forward and notching goals too.
7. Paul Pogba
Played 90 minutes for France during the international break and United will be hoping to see a fully fit and firing Pogba for the business end of the season....starting against Brighton
8. Fernandes
Just a delight watching this guy play. Top class. Scored the 100th winner against Brighton in the reverse fixture