The Italian has left Spurs by mutual consent after 16 months in charge.
His assistant Cristian Stellini has been named as interim head coach for the rest of the campaign.
The 53-year-old branded his players ‘selfish’, and savaged the club’s culture, in the wake of Tottenham’s 3-3 draw at relegation-threatened Southampton in their last league game before the international break.
The north London club are fourth in the Premier League, but have been knocked out of all cup competitions.
In a statement posted on Tottenham’s website, chairman Daniel Levy said: “We have ten Premier League games remaining and we have a fight on our hands for a Champions League place. We all need to pull together. Everyone has to step up to ensure the highest possible finish for our club and amazing, loyal supporters.”
Here’s who could be the next man in charge at the Tottenham Hotspur Stadium, courtesy of Paddy Power.
13. Marco Rose - 33/1
Former Borussia Dortmund and Borussia Mönchengladbach manager Marco Rose has been in charge of RB Leipzig since September 2022. The German won two Austrian Bundesliga titles and an Austrian Cup while in charge of Red Bull Salzburg between 2017 and 2019 Photo: Christof Koepsel/Getty Images
14. Cristian Stellini - 33/1
Cristian Stellini has previously worked as Antonio Conte's assistant at three clubs - Juventus, Internazionale and Tottenham Hotspur. Stellini took over as Spurs manager on a temporary basis while Conte recovered from gallbladder surgery in February. Stellini masterminded a 1-0 home win over Manchester City but returned to his post following Conte's recovery. Conte took charge of two further game before continuing his recuperation in Italy. Stellini took charge again and led Tottenham to a pair of 2-0 victories over London rivals West Ham United and Chelsea. Stellini was named Spurs interim head coach until the end of the 2022/23 season following the dismissal of Conte Photo: Clive Rose/Getty Images
15. Kjetil Knutsen - 50/1
Kjetil Knutsen led Bodø/Glimt to their first ever Norwegian national league title in 2020, in a record-breaking season where they lost only one game. The 54-year-old then led led Bodø/Glimt to their second Eliteserien triumph the following year. He took Bodø/Glimt to the club's first group stage in Europe in 2021, where his outfit became the first team in history to score six times against a José Mourinho side in a 6–1 victory against AS Roma in the UEFA Europa Conference League Photo: DANIEL LEAL/AFP via Getty Images
16. José Mourinho - 66/1
Would José Mourinho entertain a return to Spurs? His sacking in 2021 - despite guiding Tottenham to the League Cup final - marked the first time the Portuguese manager had departed a club without winning a trophy since 2002. The 60-year-old lifted six titles at FC Porto - including the UEFA Champions League and UEFA Cup - eight trophies across two spells at Chelsea, five titles at Internazionale - including the UEFA Champions League - and three cups at Real Madrid and Manchester United respectively. Mourinho has already won a title at his latest club, AS Roma. He took home the UEFA Europa Conference League last season, ending Roma's 11-year trophy drought and becoming just the third manager to have won all three existing major European trophies Photo: Adam Pretty/Getty Images