Roberto De Zerbi's men will look to respond positively from their 5-1 thrashing against Everton at the Amex Stadium last Sunday. The defeat dented Albion's hopes of Europe but they remain in seventh place and still fighting to compete on the continent for the first time in their history. Liverpool, Man United, Tottenham and Aston Villa are all competing alongside the Seagulls to take those prestigious slots.
De Zerbi said: "We have to remember this game because it can be a very important day for us if we improve in mentality. We have to be ready to play one game every three or four days if we want to fight for our big target."
Albion certainly have some tricky matches on the horizon as they face three clubs currently in the top three from their remaining five fixtures.
Here's how you can follow Albion's last five matches and the ones selected for live TV...
5. Aston Villa v Brighton
Sunday May 28. Albion's final match of the campaign kicks off at 4.30pm from Villa Park. The match will not be broadcast live and highlight can be seen on Match of the Day. Photo: Christopher Lee