In their final home game of the season, Albion were facing a City side who had already been crowned champions and had a guard of honour before the game.
An exhilarating first-half saw huge chances at both ends, with both teams playing some superb football.
Brighton created some big opportunities to open the scoring, with Danny Welbeck coming the closest with a free-kick striking the crossbar.
Man City were always a threat up the other end with Erling Haaland missing two great chances before he unselfishly turned provider for Phil Foden who made it 1-0.
Albion responded well and thought they had quickfire equaliser after Kaoru Mitoma bundled the ball in from a corner – but VAR adjudged it to be handball.
Undeterred, Albion continued to cause City problems at the back and a moment of magic came when Julio Enciso took aim from 30 yards and found the top corner with a stunning strike.
Brighton were in the ascendancy and found the net again through Danny Welbeck's great finish from a tight angle. But the experienced England striker was correctly ruled offside by the linesman.
Both teams had further chances to win the game in the second-half but City were controlling possession. Haaland thought he scored the winner with a towering header but he was adjudged to have fouled Levi Colwill.
In the end, nothing could separate the sides and Brighton got the point they needed, whilst City continued their mammoth unbeaten record ahead of two cup finals.
9. Julio Enciso - 8
Brighton have another gem on their hands. The teenager was a real thorn in City's side in the first half with great link-up play. His equaliser was nothing short of exceptional. A special moment to rival his winner at Chelsea and goal of the season contender. Taken off after 50 minutes to a standing ovation Photo: Clive Rose/Getty Images
10. Kaoru Mitoma - 7
This guy never stops running. He rarely gets a rest but he always seems to be at full capacity when he puts the burners on. The Japan star put the ball in the net from a corner but it was disallowed for handball. He also saw more than one effort in the second half go just over the crossbar and another one saved Photo: Mike Hewitt/Getty Images
11. Danny Welbeck - 8
Great finish ruled out for offside. So unlucky and would have been richly deserved for his selfless play. Linked up play superbly in the first half. Mistimed a header in great position after the break Photo: Clive Rose/Getty Images
12. Evan Ferguson - 7
The youngster looks like scoring every time he gets the ball in the box. Ferguson nearly made an instant impact from the bench, with a powerful shot saved at the near post. He was nearly one-on-one later on but a heavy touch let him down Photo: Mike Hewitt/Getty Images