The Spanish outfit finished eighth in La Liga last term and will likely provide a stiff test for the Seagulls ahead of their Premier League opener at Everton on August 17.
It will give new head coach Fabian Hurzeler a chance to make his mind up on the fitness of some of his key players – many of which have not yet featured in the pre-season matches in Japan or in the 1-0 win against QPR at Loftus Road last week.
Here's the latest injury and team news ahead of the Villarreal match at the Amex Stadium on August 10 (3pm).
5. Pervis Estupinan - out
The Ecuador left back had surgery on his left ankle and will miss the start of the season Photo: PAUL ELLIS
6. Lewis Dunk - doubt
Given extended leave after his involvement with the England squad at the Euros. Hurzeler said: "I’m looking forward to seeing him back. He’s my captain and one of my leaders. He will be back on the pitch next week. Photo: George Wood
7. Billy Gilmour - doubt
Has not featured at all in pre-season following his Euro 2024 involvement with Scotland. Continues to linked with a move to Napoli. Hurzeler said he's expected to be back training this week Photo: Charlie Crowhurst
8. Joao Pedro - doubt
The Brazilian is back on the training pitch but has yet to feature in pre-season with an unspecified injury Photo: Mike Hewitt