This evenings visitors have never previously won at Old Trafford but Graham Potter's team will arrive full of confidence having won their lasttwo Premier League matches against Southampton and Newcastle.
United could however be without without striker Anthony Martial (knee) and defender Victor Lindelof (back). Both are doubts having missed training on Friday morning, while Solskjaer will also assess the fitness of Marcus Rashford and Mason Greenwood
Paul Pogba could also return to the line-up having completed 90 minutes for France during the international break.
Scroll down and click through to see how United could line-up for this one
1. Dean Henderson
The fierce competition between the sticks continues and Henderson could well get the nod for this one ahead of David de Gea
2. Wan-Bissaka
Looking more and more comfortable in Man United shirt as the season progresses and will take his place at right back
3. Axel Tuanzebe
Could well be brought in to partner Harry Maguire at the heart of the defence in Victor Lindelof 's absence
4. Harry Maguire
The United skipper is back to his best and a formidable barrier in the United rearguard